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Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is an experimental compound derived from angiotensin IV, initially studied for its potential to enhance cognitive function and repair neurological damage. While preclinical research is intriguing, no human trials have been conducted, and its safety, efficacy, and long-term effects remain unknown. Below is an overview of its proposed benefits, limitations, and risks:
Purported Benefits (Based on Preclinical Studies)
1. Cognitive Enhancement:
– Memory & Learning: In animal studies, Dihexa demonstrated potent neuroprotective effects and improved memory retention by promoting synaptic plasticity. It activates the hepatocyte growth factor (HGF) system, which supports neuronal repair and survival.
– Neurodegenerative Disease Potential: Hypothesized to slow progression of Alzheimer’s, Parkinson’s, or traumatic brain injury by repairing damaged neurons.
2. Mood Regulation:
– Animal research suggests Dihexa may reduce anxiety and depression-like behaviors by modulating neurotransmitter systems (e.g., dopamine, serotonin).
3. Neurogenesis:
– May stimulate the growth of new neurons (neurogenesis) in the hippocampus, a brain region critical for memory.
*Note: This summary is for educational purposes. Experimenting with unregulated research chemicals carries significant health risks.*
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